23
Oct
TUBARIAL SALIVARY GLANDS
TUBARIAL SALIVARY GLANDS
Science & Technology | Mains Paper-III
Scientists in the Netherlands have discovered a potential new organ in the human throat that they stumbled upon while carrying out research on prostate cancer.
Tubarial Glands
- The salivary gland system in the human body has three paired major glands and over 1,000 minor glands that are spread throughout the mucosa.
- These glands produce saliva necessary for swallowing, digestion, tasting, mastication and dental hygiene.
- When researchers were studying scans from about 100 people, they found a bilateral structure at the back of the nasopharynx and these glands had characteristics of salivary glands.
- Researchers have proposed the name “tubarial glands” for their discovery.
- The researchers believe that these glands would qualify as the fourth pair of major salivary glands.
- The proposed name is based on their anatomical location; the other three glands are called parotid, submandibular and sublingual.
Why are these glands being discovered only now?
- The location of these glands is at a poorly accessible anatomical location under the base of the skull, which is an area that can only be visualized using nasal endoscopy.
- Further, conventional imaging techniques such as a CT scan, MRI and ultrasound have not allowed the visualization of these glands.
- For the scans done on the 100 patients, a new type of scan called the PSMA PET/CT scan was used, which was able to provide the high sensitivity and specificity required to detect these glands.
What is the purpose of these glands?
- So far, researchers suspect that the physiological function of the glands is to moisten and lubricate the nasopharynx and the oropharynx.
- However, this interpretation needs to be confirmed with additional research.
Significance of this discovery
- The discovery is potentially good news for some cancer patients with head and neck cancers.
- Patients with head and neck cancers and tumours in the tongue or the throat are treated with radiation therapy that can damage the new salivary glands, whose location was not previously known.
- Oncologists will be able to circumvent these areas and protect them from the side effects of radiation which can lead to complications such as trouble speaking, swallowing and speaking.
- Some patients may even face an increased risk of caries and oral infections that can significantly impact their life.
PSMA PET-CT technology
- The new organ was discovered while scientists were studying prostate cancer cells using PSMA PET-CT technology — a combination of CT scans and positron emission tomography (PET) — which is good in detecting salivary gland tissues.
- In this technique, a radioactive “tracer” is injected into the patient that binds to the protein PSMA, which is elevated in prostate cancer cells.
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